Dupuytren’s disease, a clinical entity originally described more than 400 years ago, is a progressive disease of genetic origin.
It is characterized by thickened and contracted palmar fascia leading to contractures of fingers which lead to limited function.
The pathophysiology is multifactorial and factors thought to be involved are genetic predisposition, trauma, inflammatory response, ischemia, and environment, all play a role in the disease process. Management is based on level of contracture and may be surgical or nonsurgical.
Treatments of severe disease include open release; fasciectomy or fasciotomy. Postoperative management focuses on maximizing range of motion through extensive physiotherapy.